The test identifies specific antibodies for Yersinia enterocolitica in IgA and/ or IgG class in human plasma. Infection with a pathogen with children and youth most frequently appears as enteritis, stomachache, fever and diarrhea and it also may show alleged symptoms of appendicitis. In case of adult people it may show as ileitis and colitis. Non-treated infection may develop into a reactive arthritis or erythema nodosum.
The most frequent way of infection transmission is the alimentary tract. In case of acute primal infection without complication, the level of antibodies IgA drops down within a few weeks or months to an undetectable level. Secondary immunology complications, such as arthritis or erythema nodosum are connected with constantly increased level of IgA antibodies. Antibodies of class IgG, which develop at a later stage constitute another, more specific weapon in the struggle with the pathogen.
Normally, antibodies of this class remain for a longer time in the serum (plasma) and may be detected even 12 months after a contact with the pathogen. In the chronic course of the disease or in case of immunology disorders antibodies of class IgG and IgA are present in the serum for an even longer period of time. It should be remembered, however, that an immunology response normally comes after 3-4 weeks, which means that serology tests are of little value in diagnosing early stages of the disease. On the other hand, the presence of antibodies (class IgG) may prevail for years and that is why the test cannot be used for treatment monitoring.
Sample type: plasma, serum
Delivery and storage: at 4-8°C
Testing method: ELISA
Turn out time: up to 7 work days