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Bartonella henselae (Bartonellosis) – quality + quantity Real-Time PCR (RUO/153)

Molecular diagnostics which is based on PCR methods (e.g. Real Time - PCR) is a sensitive test, whose primary limitation is difficulty in appropriate material selection. According to the recommendations the biopsy of skin lesions is the best material to make this test but analysis of systemic fluids such as: urine, blood or cerebrospinal fluid is also accepted. It should be remembered, however, that probability of bacteria detecting in systemic fluids is lower due to less frequent presence of this pathogen in the analyzed sample.

CB DNA test services include of all RUO (Research Use Only) tests which are designed only for the research purposes. Result of this tests is only for informational purposes and does not have a diagnostic test status.

The test allows the ability to detect the presence and/ or determine the amount of DNA copies of Bartonella henselae bacteria, transmitted onto humans mainly by arthropods feeding with the mammal blood (hematophagous animals), e.g.: ticks, lice or fleas.

One can also get infected as a result of scratching or a bite from an infected animal, most often a cat or a dog (that is why it is colloquially called a "cat scratch disease"). Bartonella henselae is an intracellular parasite located in erythrocytes.

In case of humans, the disease initially proceeds asymptomatically or only with local symptoms around a wound (local reddening, inflammatory papule). With some people, after a few weeks of the infection start a fever comes up, lymphadenopathy; possibly some other sickness symptoms (headaches, backaches, hypogastrium pains, fatigue). Untreated infection may cause recurring fevers and may lead to the inflammation of the brain or heart.

Test material:            whole blood (EDTA)

Transfer method:      temp. 4-8°C

Testing method:        Real-Time PCR

Delivery date:            up to 7 working days (for an extra fee /200zl/ the delivery date is up to 48 hours after delivery sample to the laboratory)